The only disadvantages that occur to me are: (1) they require regular attention (feeding and watering), (2) need someone to take care of them when you are away on holiday, (3) outgrow their pots, become root-bound and need to be potted on, and (4) sometimes flourish so well that they eventually require a pot that is too large for the situation in which they are placed (eg a narrow window shelf).
Certainly, the leaves of some species, such as aspidistras and rubber plants, need to be cleaned occasionally, because they are fairly broad and accumulate dust, and this is easily done by wiping them gently with a damp cloth. Spraying before removing the dust is not a good idea, as the dust won't all be removed and, over time, is likely to form a 'skin' on the leaf surface, which will reduce the amount of light it receives.
It's important to water pot plants thoroughly (until water drains out of the bottom of the pot), otherwise they will be encouraged to surface-root in search of water and become stressed. You can stand your pots in the sink to drain them after watering and then place them on trays or, if small pots, on saucers.
When I started keeping house plants, I found the following guide invaluable; I would strongly recommend it - if it isn't available where you are, you could probably order it online: "The New House Plant Expert", by Dr.D.G.Hessayon (pbi Publications). The one I have was published in 1996, but there is likely to be a more up-to-date edition. Good luck with your indoor gardening!